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Pajk T, Rezar V, Levart A, Salobir J

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10.1161/01.str.31.2.347 Stroke 29 de VriesH

Exosomes measuring 40100 nm are widely present in the emulsion

Despite this, a substantial body of pre-clinical and limited clinical research has mapped DSIPs pharmacological effects across multiple systems, identifying several probable mechanistic axes including NMDA receptor modulation, adrenergic system regulation, MAPK/ERK cascade interaction, and mitochondrial respiration effects while acknowledging that the existence of an undiscovered DSIP-like endogenous peptide(s) may account for part of the DSIP-like immunoreactivity observed in tissue distribution studies