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The STEP UP trial, a Phase 3b study published in The Lancet Diabetes & Endocrinology in 2025, evaluated a 7.2 mg weekly injection dose in over 1,400 adults with obesity (BMI of 30 or higher) and without diabetes

Researchers have also identified numerous modifiable factors with strong evidence connecting them to lower risk of cognitive decline and dementia (see Figure 2, page 12)

Vascular and angiogenic research represents a third major thread

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Vitamin B12 is an essential vitamin thats found in several animal-based foods, including meats and many dairy products