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Demyelinated axons are prone to damage, so the loss of oligodendrocytes may lead to secondary axonal injury ( Cells Death Excessive iron can lead to cell death

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Targeting the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling pathway may enhance the detoxification capabilities of choroid plexuses that are linked to glutathione conjugation, but little is known about mechanisms of enzyme induction in this tissue

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