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Other supporting ingredients such as niacinamide, botanical extracts, hydrators, etc., to soothe, protect, and improve overall skin feel

[PubMed: 16646688] 382

doi: 10.1016/j.cell.2017.09.021 26 LeeSHwangNSeokBGLeeSLeeSJChungSW

[DOI] [PubMed] [Google Scholar] 92.Harrison S.A., Manghi F.P., Smith W.B., Alpenidze D., Aizenberg D., Klarenbeek N., Chen C.-Y., Zuckerman E., Ravussin E., Charatcharoenwitthaya P., et al

Our results demonstrate that pyridoxine, also known as vitamin B 6 , induces GSH synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection