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Given that erectile dysfunction is often a symptom of systemic vascular issues (like endothelial dysfunction), a systemic treatment makes a great deal of sense

Garcia-Maurino S, Gonzalez-Haba MG, Calvo JR, et al

Enrolling 17,604 adults aged 45 or older with established cardiovascular disease and a BMI of 27 or higher (without diabetes), SELECT showed that semaglutide 2.4 mg reduced the composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke by 20% over a mean follow-up of nearly 40 months

Your hormones during perimenopause are chaoticestrogen can spike high, plummet low, surge again

Lower starting points (around 1 mg/day) are typical for new research planning, and 2 mg/day is the high end most references cite