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(C, E, F) Values are the mean of at least three independent replicates

Estrogen Metabolism Support Optimizing hepatic Phase I and Phase II estrogen detoxification reduces the burden of potentially carcinogenic estrogen metabolites (particularly 4-OH and 16-OH estrone) and may reduce estrogen-driven fibroid growth: DIM (diindolylmethane): Shifts estrogen metabolism toward the favourable 2-OH pathway Calcium-D-glucarate: Inhibits -glucuronidase, preventing deconjugation and reabsorption of estrogens in the gut (Note: off-the-shelf detox kits from health food stores are not equivalent to therapeutic doses of these specific compounds) N-acetylcysteine (NAC): Supports glutathione synthesis and Phase II sulphation 3

Measurement of serum creatinine and cystatin C are more convenient and rapid tests for evaluating kidney function

However, when the production of ROS exceeds the capacity of the antioxidant defense system, oxidative stress emerges, which contributes to the pathogenesis of numerous diseases [3]

It is the "migraine hangover" (postdrome) that leaves you feeling like a ghost in your own life even after the pain stops