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Individuals receiving therapeutic B12 injections or taking high-dose oral supplements without medical supervision face the greatest risk of very high levels

Additionally, the two most commonly used ELISA kits for pro-BDNF referenced in the literature were also tested (Supplementary Table S1), namely, the high sensitivity pro-BDNF human ELISA kit (Cat

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Nuclear PQC is therefore primarily focused on proteins that become misfolded via damage during or after nuclear import, and it is thought that it may have evolved to target specific features of damage-induced misfolding that are particularly harmful in the nuclear environment

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