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This ratio (1.66) was used to calculate the overall number of genes that affect GHK at various cutoff points (rather than probe sets)

63 Moreover, mucosal inflammation in claudin-7 KO mice appears to be a product of epithelial cell instability and not necessarily the result of barrier deregulation, given that no apparent gut leakiness was documented at early time points in these mice

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Biological replicates, isotope-labeled internal standards, and repeated QC checks are used to separate true biological differences from analytical noise, enabling more reliable biological interpretation

Subsequently, the second GSH molecule can bind to the H-site and the H-site bound GSH is deprotonated into the GS form