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Contamination, endotoxins and incorrect reconstitution can all cause problems ranging from injection site reactions to systemic infection

Gently swirl or invert to dissolve do not vortex or shake vigorously, as this can disrupt the disulfide bond and active loop conformation

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No interaction between the two compounds affects dosing timing

Besides, the nNOS isoform also plays a significant role in the pathophysiology of irritable bowel syndrome (IBS) and other gastrointestinal disorders, including IBD