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In addition, GSSG retained in mitochondria during oxidative stress can lead to the S-gluthionylation of target proteins with mitochondrial dysfunction (20, 21)

Kanon, University College Cork, Ireland Federica Conti, Parker University, United States Updates Copyright 2026 Anlacan, Jamora, Krattinger, De Longis, Hartweg, Steinmann and Trov

Mitochondrial dysfunction and oxidative stress in metabolic disorders - a step towards mitochondria based therapeutic strategies

Commonly used in vitro cell culture models are 2D monolayer and 3D cell pellet, filter, or alginate bead cell culture (Figure 2)

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