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published dosage figures refer to experimental animal/in-vitro studies, not human protocols

Specifically, it significantly increases the production of Type I and III collagen, as well as elastin, in fibroblasts

For skin tightening, we do see that patients with mild skin laxity can get great results from a single treatment, whereas those patients with more severe skin looseness and textural issues may need more

study, effects in fast-aging mice were observable within 10-14 days of treatment initiation