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The use of a iPSC-derived BBB model would also pave the way to the introduction of immune components, such as microglia, which could help in more closely mimicking the barrier and the tumor microenvironment, and how immune responses may affect barrier tightness and permeation characteristics

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Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations

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It is a synthetic tetrapeptide that is studied in relation to compounds derived from the pineal gland

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