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The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice

For both Most Studied Pathways and Gene-Associated Pathways, the threshold of rank 30 was chosen to balance sensitivity and specificity, capturing pathways with substantial evidence while minimizing the inclusion of less relevant ones

Intracellular ROS and lipid peroxidation level Reactive oxygen species (ROS) were measured on the basis of the intracellular peroxide-dependent oxidation of DCFH-DA (S0033S, Beyotime) to form the fluorescent compound 2,7-dichlorofluorescein (DCF)

Neurol Ther 9:395402

Lipotropics are known to aid in the breakdown of fat in the liver, supporting weight management and liver health