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doi: 10.1172/JCI169671

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Nephrotoxicity and renal pathophysiology: A contemporary perspective

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This SUMOylation prevents p300 from accessing C-terminal lysines and represses transcriptional activation, thus promoting cell proliferation by inhibiting the antigrowth function ( SUMOylation is also implicated in ferroptosis (Stockwell et al., 2017) and is hyperactive in many cancers (Sheng et al., 2021)

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This hinders drawing conclusions for the general population

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A 2023 study published in Pharmaceuticals (Basel) found that it may help with brain-gut axis repair and function ( 9 )

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