Redox-associated metabolic responses By the age of 12-mo, commensals anaerobes (e.g., Bifidobacterium, Bacteroides , Clostridium ) are colonized 1001000 times more frequently than aerobic bacteria due to a substantial increase in the populations of facultative bacteria throughout infancy (e.g., Enterobacteriacea e, Enteroccocus , Streptococcus ) 87
doi: 10.1016/j.healthplace.2022.102895 3
Deficiencies or imbalances in these elements have been linked to metabolic syndrome and PCOS, likely due to their roles as cofactors for antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (Gpx) reactions 16
Immune system aging might be one of the main drivers of systemic aging-related functional decline at the organismal level across organisms 4,66,67
Proposed mechanisms include: DSIP-induced upregulation of downstream receptor systems that outlast the peptide itself