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Conversely, if GSSG oxidizes PDI, then the net result would be an increase in the concentration of GSH relative to GSSG

The significant increase in plasma vitamin B6 in many children with autism spectrum disorders [73, 76, 87, 92, 93] could potentially reflect diminished cellular uptake or inefficiency of cells to retain or store B6

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[] As a matter of fact, encephalopathy and peripheral neuropathies arising from exposure to these heavy metals may occur anywhere from a few hours to a few days after acute exposure to a high dose

Obstet Gynaecol Reprod Med 28:714