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Some patients report a pale or yellowish tinge to the skin, and glossitis (a sore, red tongue) may develop

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It can reduce the expression of breast cancer-related receptors EGFR and ER and induce the G2/M phase arrest (Khamis et al., 2018)

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A variety of surgical treatment options may be considered, including biopsy of the tissue or sentinel node, enlargement of the resection, dissection of the lymph nodes, and in-transit metastasis removal [217, 218]