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UK guidance (MHRA and NICE) advises checking B12 levels in patients on metformin who develop symptoms of deficiency (anaemia, neuropathy) and considering periodic monitoring in those on long-term therapy

doi:10.1210/js.2019-00078 Gilbert EW, Tay CT, Hiam DS, Teede HJ, Moran LJ

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Sample Collection: Depending on the service, you may receive a home testing kit or be directed to a local lab for sample collection