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Schildknecht S, Ullrich V

However, GPNAs high toxicity of GPNA limits its use in cellular experiments, and the mechanism of V-9302 inhibition is controversial and requires further investigation [80]

The gene encoding DSIP has not been identified in any species

In Se deficiency, GPx activity decreases, degradation of H2O2 is reduced, thyroid cells are less resistant to oxidative stress, apoptosis and cell death occur ( 3 Se deficiency is one of the risk factors for many thyroid diseases 3.1 Se and Graves disease The main clinical manifestation of Graves disease (GD), also known as toxic diffuse goiter, is thyrotoxicosis caused by excessive production of thyroid hormones

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