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Also supporting the hypothesis of involvement of an oxidant stress in hyperhomocysteinemia-mediated vascular disorders, an increase in plasma and aortic thiobarbituric acid reactive substances was related to the occurrence of atherosclerotic lesions in animals fed a methionine-enriched diet (Matthias et al, 1996

This trigger increased ROS production and pro-inflammatory cytokine release, ultimately exacerbating neurotoxicity (Trudler et al., 2014)

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Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance