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Researchers have estimated that cigarette smoke has 7,357 chemical compounds from many different classes (Rodgman and Perfetti 2009)

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Complex tobacco blend : The cigarette uses a mix of Virginia, Burley, and Oriental tobaccos, creating layered notes that feel both earthy and aromatic

Marijuana is known to cause dry mouth by reducing saliva flow

Most recently, electronic cigarettes, which vaporize a nicotine solution, have gained increasing popularity and generated concern among public health practitioners, particularly with regard to effects on youth