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In cases of advanced periodontal disease, receding gums can be severe and large parts of the tooth roots may become exposed and the gum papilla may also recede, causing a sensitive tooth

Tissues were obtained through the National Disease Research Interchange (Philadelphia, PA) with approval from the University of Pittsburgh Committee for Oversight of Research and Clinical Training Involving Decedents (CORID)

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The documented per-dose amounts (150 mcg from the 10 mg vial

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