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Increasing levels of VitB12 in humans have been shown to lead to a decline in 24-h mean melatonin levels and nocturnal melatonin levels during bright-light exposure, thereby disrupting the sleep-wake cycle toward increased alertness and decreased sleep duration [21, 38]

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Research indicates DSIP may promote slow-wave sleep, modulate pituitary hormone secretion, and exhibit stress-protective and antioxidant properties