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Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg
Useful for determining protein and peptide topology on the cell surface
and a C-terminal region
5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent
Erythroferrone/Myonectin acts as an endurance exercise-driven myokine which protects the heart from ischemic injury by reducing cardiomyocyte apoptosis and macrophage inflammatory response
Adezmapimod Pack Size:5 mg Bafilomycin A1 (BafA1) is aAdezmapimod (SB 203580) is a selective and ATP competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a p38 and SAPK2b p382, respectively. Adezmapimod inhibits LCK, GSK3 and PKB with IC50s of 100 500 fold higher than that for SAPK2a p38. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator.