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Specifically, we focus on the biochemical and molecular mechanisms through which AST influences cellular processes, including oxidative stress reduction, modulation of neuroinflammation, and protection against neuronal damage

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[iv] Finally, a number of additional factors may influence the design of first-in-human clinical trials, including the presence or absence of biomarkers, the suitability of the selected preclinical models, and the demographic characteristics of the study participants

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