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Lisa, as somebody that I feel this probably hit home, just like you and Dave, I think you see this a lot with your population

To mitigate any potential negative effects on methylation, additional interventions can support the methyl cycle while using folinic acid therapy: Improving SAH (S-adenosylhomocysteine) levels by reducing homocysteine through methyl donors like betaine (TMG), vitamin B6 (P5P), and methylcobalamin (B12)

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Acknowledgments We thank the members of Chan Lab for critical comments on this manuscript

Weve shared important tips for adults, like the right amount to take and how often