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Plateau typically around week 40-48

Change in colour was measured at 532 nm

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LA can also decrease hepatic damage in the process of steatosis by inhibiting inflammation (by reducing the expression of high-mobility group protein box-1 [HMGB-1], Toll-like receptor-4 [TLR-4], vascular cell adhesion molecule-1 [VCAM-1], and COX-2)

In patients with acute coronary syndrome, berberine adjunctive to standard care reduced inflammatory markers including matrix metalloproteinase (MMP)-9, intercellular adhesion molecule (ICAM)-1, and vascular cell adhesion molecule (VCAM)-1 (10)