The authors reported that in obese mice, daily AOD-9604 administration over 14 days produced significant reductions in body weight gain, decreases in adipose tissue mass, and increases in fat oxidation, with effect sizes comparable to those of full-length human growth hormone [1]
Research involving multiple metabolic-, mitochondrial-, or stimulant-related compounds may warrant additional caution and individualized evaluation in experimental settings
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Storage follows standard peptide and small molecule handling: Keep the solid form at or below -20C in a cool, dark, dry place
Unlike earlier compounds that affected multiple methyltransferases, 5-amino-1MQ demonstrates remarkable specificity for NNMT without inhibiting related SAM-dependent enzymes or components of the NAD+ salvage pathway