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While the canonical circuit and the initial study of Rosenberg and colleagues (Rosenberg et al., 2000) would suggest that occipital Glx should be normal in OCD, one study in adults found a strong negative correlation between OCD symptomatology and occipital Glx (Starck et al., 2008)

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Fumagalli F, Di Pasquale L, Caffino L, Racagni G, Riva MA

As mentioned above, one of the ways that cells can enter senescence is when their telomeres are shortened beyond usefulness the cell may (or may not) still be working well, but it has lost the ability to divide

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