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A2A receptor activation upregulates vascular endothelial growth factor (VEGF), promotes angiogenesis in the dermal microvasculature, stimulates fibroblast migration and proliferation, and suppresses inflammatory cytokine release

Human evidence is limited to a handful of small studies for BPC-157 and even less for the rest, long-term safety data doesnt exist, and the compounds sit in a regulatory grey zone that may shift through 2026

2) Applications: - Post-procedure recovery (e.g., post-laser, microneedling)

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