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After 1 month of treatment in pernicious anemia patients, the once weekly dosing of 500 mcg B12 intranasal gel resulted in a statistically significant increase in B12 levels when compared to a once monthly 100 mcg IM dose

4 Aside from those with genetic methylation defects in the metabolism of vitamin B12 and folic acid, our patients have excellent results with a sublingual vitamin B12 that dissolves slowly under the tongue

Our providers carefully monitor these patients to determine the most beneficial frequency, usually ranging from once every one to three months depending on individual needs

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