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These are the most common symptoms for B12 deficiency: Low energy, and it doesn't really get better when you sleep Numbness or tingling in the hands and feet Memory problems, difficulty focusing, "brain fog" Changes in mood, like irritability or feeling down Weak in the muscles, or overall weakness Some folks near the Inlet Square area come in because their balance feels slightly off

The focus on these specific strategies in research and therapeutic development highlights their potential to significantly enhance efficacy and outcomes

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We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)

Combined use should always follow clinical assessment and should not replace investigation of underlying causes