Low glutathione levels are found in people with lupus, rheumatoid arthritis (RA), Crohns disease (IBD), multiple sclerosis (MS), and psoriasis.[ref] Related articles: Lupus, Rheumatoid arthritis, IBD, MS, and psoriasis genes Cystic fibrosis: People with cystic fibrosis, which is a genetic disease caused by mutations in the CFTR gene, have frequent respiratory infections that cause lung inflammation and produce oxidative stress in the lungs, which depletes glutathione levels
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The oxidative stress is a predisposing factor to skin issues such as premature skin aging, wrinkles, inflammation, and pigmentation imbalances because it establishes an imbalance between the natural antioxidants of the skin and free radicals, including reactive oxygen species (ROS)
The research timeline can be found in Fig