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doi: 10.1097/MOT.0000000000000313 164

Additionally, BDNF increases could represent a pathophysiological response to neurotoxic effects of cocaine

Common Topical Application Patterns Use case Facial anti-aging (community use) Concentration 1-2% Frequency Once or twice daily Cycle length 8-12 weeks Use case Scalp / hair-research interest Concentration 1-3% Frequency Daily Cycle length 12+ weeks ongoing Use case Compounded post-procedure Concentration 1-2% Frequency Per clinician guidance Cycle length Per clinician guidance Topical concentrations are typically expressed as percent weight

The SURPASS and SURMOUNT programs collectively demonstrate tirzepatide as a transformative therapy for cardiometabolic disease