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GST-tagged SF3B1(1463) was eluted eight times with 750 l of elution buffer (50 mM Tris, 20 % glycerol, 150 mM NaCl, 0.5 mM EDTA, 10 mM glutathione)

Pairing Glutathione with Other Nutrients Vitamin C: Helps regenerate glutathione and enhances its antioxidant effects

FBXW7 contains a dimerization domain (DD), an F-box domain, and multiple WD40 repeat domains that mediate substrate binding (Fig

We then performed single or combination treatment using the GLUT1 inhibitor BAY-876 and YBX1 inhibitor SU056