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Standard medical practice

Possible mild side effects include injection site irritation, headaches, or flushing

This leads to a reduction in ovarian reserve and a higher occurrence of chromosomal abnormalities especially aneuploidy in oocytes 3,4 , increasing the risks of infertility, pregnancy loss, perinatal mortality, and congenital disorders in women at an advanced age 5,6

As the kinetics of these transporters slow with decreasing temperature 59 , it is possible that supercooled storage of RBCs decreases the demand for ATP-mediated ion homeostasis, thereby maintaining ATP levels and obviating 2,3-DPG catabolism

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