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Mitochondrial dysfunction in pathophysiology of heart failure

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Limited spectral dispersion: due to the relatively uniform environments experienced by residues within IDPs/IDRs, their NMR spectra often exhibit poor dispersion, hindering the ability to resolve individual signals

Bioactivities of hen's egg yolk phosvitin and its functional phosphopeptides in food industry and health

This instability may result from inadequate demethylation of conserved non-coding sequence regions in the Foxp3 locus, known as the Treg-specific demethylation region (TSDR), which is fully demethylated in thymus-derived Tregs (tTregs) but often methylated in iTregs ( in vitro systems, and their physiological relevance, particularly in human disease, requires further validation