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Based on the copper content measurements, all recombinantly produced proteins ( jr PPO1-wt and five mutants) contain a similar amount of copper (~0.81.1 copper ions per protein), indicating that the changes in activity are not based on the number of copper ions in the active center

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Curcumin suppresses the induction of indoleamine 2, 3-dioxygenase by blocking the Janus-activated kinase-protein kinase C-STAT1 signaling pathway in interferon--stimulated murine dendritic cells