In contrast, several studies suggested that the activation of ERK and JNK phosphorylates MITF at Ser 73 , which leads to its ubiquitination and degradation, thus subsequently down-regulating melanogenesis (not shown in Figure 3) [26,3941]
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How AHK-Cu communicates with cells Copper peptides work through multiple signaling pathways

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Melatonin, the "sleep hormone," plays a significant role in regulating our sleep-wake cycle