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Finally, although the use of the permutation test on the mixed model estimates is likely valid given the assumed conditional exchangeability of the observations, our sensitivity analyses combining responses within each subject were not significant except for the MUC5AC/MUC5B ratios

Smoking is one of 10 modifiable risk factors for stroke Smoking accounts for around 90% of the risk of stroke

Smokers may be discouraged from quitting as many still believe that filtered cigarettes protect their health, and young people may find it easier to inhale their first puff with filtered cigarettes

It also varies from person to person

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