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nanomolar in cell culture Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, receptor density, pharmacokinetics, peptide degradation rates, and PepT1 expression patterns

Combined-mechanism research typically positions the three compounds as engaging non-overlapping pathways rather than as synergistic compounds a research-context distinction that matters for experimental interpretation

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Moses MA, Wiederschain D, Loughlin KR, Zurakowski D, Lamb CC, Freeman MR