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Primary markers include IGF-1, fasting insulin, and targeted metabolomic panels evaluating oxidative phosphorylation byproducts

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3.1.1 Topoisomerase inhibitors Topoisomerase inhibitors are a class of anticancer drugs whose mechanism of action is based on blocking topoisomerase enzymes from re-ligating the DNA strands after supercoiling, thus preventing DNA replication [61]

Most people receive this amount of intake if they follow a healthy diet