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Most effective clinical options include: Hydroquinone (4%) remains the gold standard to treat hyperpigmentation Q-switched lasers break down melanin deposits effectively Chemical peels with specific acids remove pigmented layers Newer treatments like tranexamic acid and cysteamine cream have fewer side effects Can home remedies really reduce melanin levels

Although such strategies are promising, the evidence base remains limited, and additional studies, including clinical trials, are needed to establish feasibility, safety, and durability of benefit in humans

For instance, according to the WHO statistics reported in September 2022, Non-communicable diseases (NCDs) kill 41 million people each year, equivalent to 74% of all deaths globally