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Furthermore, the BDNF polymorphism has been linked with disease severity, early adolescent onset, a propensity toward rapid cycling, and greater cognitive and executive function deficits in bipolar disorder (5356)

18 Expert Group on Vitamins and Minerals

Metabolic Support B12 contributes to healthy metabolism through several pathways: Assists in converting food to energy rather than stored fat Supports thyroid function, which regulates metabolism Helps maintain efficient cellular energy production Provides energy needed for physical activity This metabolic support can complement weight management efforts as part of a comprehensive approach

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It said its consultations encouraged shared decision-making, where individuals are given balanced information on potential mechanisms, theoretical benefits and uncertainties