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doi: 10.1097/BOR.0000000000000476 [DOI] [PubMed] [Google Scholar] 224.Perez-Ruiz F, Dalbeth N

Various species of Lactobacillus exert effects on the expression and secretion of mucins

Academics have noted that most experimental peptides have little scientific evidence to support the claims being made, and where studies do exist these are often in animals or cells

The honest summary: the three peptides individually sit somewhere between "intriguing preclinical compound with biological plausibility" and "early-stage research chemistry with insufficient human data." The blend is a research convenience, not an evidentiary upgrade

This is often quite generalised, and can affect the hands and wrists like any other area