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No serious adverse events were reported in healthy adults

From an early stage, highly concentrated Prx2 is necessary in the erythropoiesis process, particularly in the erythroblast, acting as an antioxidant when Hb synthesis is at its peak and large amounts of heme and iron are handled

98,99,100 Under oxidative stress conditions, ROS may also interfere with mtDNA replication and repair mechanism

IV therapy is ideal if oral intake isnt possible, speed is essential, or symptoms are severe

Thus, to definitively determine if late-life pharmacologic modulation of IGF-1R signaling could improve survival, we performed a longevity study in female mice with lifelong i.p