Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging
Cognitive symptoms at midlife often connect to thyroid function, testosterone, sleep, or metabolic health, so a responsible plan looks at those drivers rather than reaching for one peptide first
Studies on human skin fibroblasts (Moeller et al.) have demonstrated T3 activating effect on numerous enzymes of the glycolysis pathway, as well as: an increase in mRNA for the hypoxia-inducible transcription factor 1-alpha (HIF-1) a key factor in the regulation of glycolysis, an increase in mRNA for the Glucose Transporter Type 1 (GLUT1) transporter, and an increase in mRNA for the Solute Carrier Family 16 Member 3 (SLC16A3) lactate exporter [23]
It is not a reasonable extension of an anti-aging protocol, and I do not endorse it
As skin ages, it makes less collagen and elastin, which leads to fine lines and a loss of firmness