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(PubMed) Watkins D, Rosenblatt DS

Warnings Benzyl Alcohol Patients who have early Leber's disease (LHON) a hereditary disease that causes optic nerve atrophy have been found to suffer severe and swift optic atrophy when treated with vitamin B12

Research on CJC-1295 is primarily preclinical, with most studies conducted in animal models

When shots make sense (and when they don't) Injections are the right call in specific situations: confirmed severe deficiency, pernicious anemia (where intrinsic factor is absent), or documented malabsorption that has failed to respond to oral supplementation

Based on the typical drug development timeline, Eli Lilly (the manufacturer) is expected to file a New Drug Application (NDA) in late 2026, with potential FDA approval in 2027 if the review process goes smoothly