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These simulations support the design of nanomaterials that not only improve penetration but also act on multiple functional components of the biofilm, enhancing therapeutic durability [239]

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Antioxidant Activity: Studies have documented GHK-Cus activation of antioxidant enzyme systems and its protective effects against oxidative stress in cellular models contributing to research interest in its potential role in cellular protection and age-related oxidative biology

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However, DNA hypermethylation status in sputum has been detected in LC patients in recent years ( SHOX2 and RASSF1A in bronchoalveolar lavage fluid has been shown to perform methylation analysis, with higher sensitivity and specificity compared to conventional cytology and serum CEA in the diagnosis of LC (Zhang et al., 2017)