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The antibody fragments are displayed on the surface of filamentous bacteriophage (M13)
defined centrifugal force and predefined duration in every experiment
Similar potency in vitro for the class I
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM
It is evolutionarily conserved and the most prominent substrate is tubulin
Erlotinib OMNI379 The antibody fragments are displayedErlotinib (CP 358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non small cell lung cancer. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper catalyzed azide alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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